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==TcrPDEC1 catalytic domain in complex with inhibitor wyq16==
==TcrPDEC1 catalytic domain in complex with inhibitor wyq16==
<StructureSection load='3v94' size='340' side='right' caption='[[3v94]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
<StructureSection load='3v94' size='340' side='right'caption='[[3v94]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3v94]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V94 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V94 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3v94]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V94 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V94 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=WYQ:PROPAN-2-YL+{[4-ETHOXY-3-(1-METHYL-7-OXO-3-PROPYL-6,7-DIHYDRO-1H-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)PHENYL]SULFONYL}CARBAMATE'>WYQ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=WYQ:PROPAN-2-YL+{[4-ETHOXY-3-(1-METHYL-7-OXO-3-PROPYL-6,7-DIHYDRO-1H-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)PHENYL]SULFONYL}CARBAMATE'>WYQ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v93|3v93]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3v93|3v93]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDEC, TcrPDEC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 TRYCR])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDEC, TcrPDEC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 TRYCR])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v94 OCA], [http://pdbe.org/3v94 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3v94 RCSB], [http://www.ebi.ac.uk/pdbsum/3v94 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3v94 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v94 OCA], [https://pdbe.org/3v94 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v94 RCSB], [https://www.ebi.ac.uk/pdbsum/3v94 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v94 ProSAT]</span></td></tr>
</table>
</table>


==See Also==
==See Also==
*[[Phosphodiesterase|Phosphodiesterase]]
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: Large Structures]]
[[Category: Trycr]]
[[Category: Trycr]]
[[Category: Chen, G]]
[[Category: Chen, G]]

Revision as of 11:42, 20 July 2022

TcrPDEC1 catalytic domain in complex with inhibitor wyq16TcrPDEC1 catalytic domain in complex with inhibitor wyq16

Structural highlights

3v94 is a 8 chain structure with sequence from Trycr. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:PDEC, TcrPDEC1 (TRYCR)
Activity:3',5'-cyclic-nucleotide phosphodiesterase, with EC number 3.1.4.17
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

3v94, resolution 2.33Å

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