Chorismate mutase: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

@@ Line 11: / Line 11: @@
 == Structural highlights ==
-The 3D structure of the complex of CHM with transition state analog shows the CHM structure containing a dimer of pseudosymmetry but only the N-terminal half contains an available active site pocket.  The transition state analog is buried in the active site pocket and forms extensive H-bond network with CHM. Arg 49 and Arg 134 which are part of this network are conserved in all the known CHMs<ref>PMID:16499927</ref>.  Overlaying the structure of the unliganded CHM with that of the complex shos a movement of the second shell residues Arg 72 and Gln 75 which can allow the entry of the transition state analog to the active site pocket.
+The 3D structure of the complex of CHM with transition state analog shows the CHM structure containing a dimer of pseudosymmetry but only the N-terminal half contains an available active site pocket. The transition state analog is buried in the active site pocket and forms extensive H-bond network with CHM. Arg 49 and Arg 134 which are part of this network are conserved in all the known CHMs<ref>PMID:16499927</ref>.  Overlaying the structure of the unliganded CHM with that of the complex shos a movement of the second shell residues Arg 72 and Gln 75 which can allow the entry of the transition state analog to the active site pocket. <scene name='91/916399/Cv/2'>TextToBeDisplayed</scene>
 ==Chorismate mutase 3D structures==