3sa3: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==Crystal structure of wild-type HIV-1 protease in complex with AG23== | ==Crystal structure of wild-type HIV-1 protease in complex with AG23== | ||
<StructureSection load='3sa3' size='340' side='right' caption='[[3sa3]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='3sa3' size='340' side='right'caption='[[3sa3]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3sa3]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3sa3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SA3 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=23X:N~2~-ACETYL-N-[(2S,3R)-4-{(1,3-BENZOTHIAZOL-6-YLSULFONYL)[(2S)-2-METHYLBUTYL]AMINO}-3-HYDROXY-1-PHENYLBUTAN-2-YL]-L-ISOLEUCINAMIDE'>23X</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23X:N~2~-ACETYL-N-[(2S,3R)-4-{(1,3-BENZOTHIAZOL-6-YLSULFONYL)[(2S)-2-METHYLBUTYL]AMINO}-3-HYDROXY-1-PHENYLBUTAN-2-YL]-L-ISOLEUCINAMIDE'>23X</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sa4|3sa4]], [[3sa5|3sa5]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sab|3sab]], [[3sac|3sac]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sa4|3sa4]], [[3sa5|3sa5]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sab|3sab]], [[3sac|3sac]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sa3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa3 OCA], [https://pdbe.org/3sa3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sa3 RCSB], [https://www.ebi.ac.uk/pdbsum/3sa3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sa3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
==See Also== | |||
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Nalam, M N.L]] | [[Category: Nalam, M N.L]] | ||
[[Category: Schiffer, C A]] | [[Category: Schiffer, C A]] |