3r6l: Difference between revisions

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==Caspase-2 T380A bound with Ac-VDVAD-CHO==
==Caspase-2 T380A bound with Ac-VDVAD-CHO==
<StructureSection load='3r6l' size='340' side='right' caption='[[3r6l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3r6l' size='340' side='right'caption='[[3r6l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3r6l]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R6L FirstGlance]. <br>
<table><tr><td colspan='2'>[[3r6l]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R6L FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASA:ASPARTIC+ALDEHYDE'>ASA</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASA:ASPARTIC+ALDEHYDE'>ASA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3r7n|3r7n]], [[3r7b|3r7b]], [[3r6g|3r6g]], [[3r5j|3r5j]], [[3r7s|3r7s]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3r7n|3r7n]], [[3r7b|3r7b]], [[3r6g|3r6g]], [[3r5j|3r5j]], [[3r7s|3r7s]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CASP2, ICH1, NEDD2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CASP2, ICH1, NEDD2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r6l OCA], [http://pdbe.org/3r6l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3r6l RCSB], [http://www.ebi.ac.uk/pdbsum/3r6l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3r6l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r6l OCA], [https://pdbe.org/3r6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r6l RCSB], [https://www.ebi.ac.uk/pdbsum/3r6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r6l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CASP2_HUMAN CASP2_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.  
[[https://www.uniprot.org/uniprot/CASP2_HUMAN CASP2_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Caspase|Caspase]]
*[[Caspase 3D structures|Caspase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Arkin, M]]
[[Category: Arkin, M]]
[[Category: Tang, Y]]
[[Category: Tang, Y]]

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