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==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor==
==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor==
<StructureSection load='3q5k' size='340' side='right' caption='[[3q5k]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='3q5k' size='340' side='right'caption='[[3q5k]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3q5k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leima Leima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q5K FirstGlance]. <br>
<table><tr><td colspan='2'>[[3q5k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leima Leima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5K FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D1U:4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-{[2-(METHYLSULFANYL)ETHYL]AMINO}BENZAMIDE'>D1U</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D1U:4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-{[2-(METHYLSULFANYL)ETHYL]AMINO}BENZAMIDE'>D1U</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3h80|3h80]], [[3q5i|3q5i]], [[3q5j|3q5j]], [[3q5l|3q5l]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3h80|3h80]], [[3q5i|3q5i]], [[3q5j|3q5j]], [[3q5l|3q5l]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMJF33.0312 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5664 LEIMA])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMJF33.0312 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5664 LEIMA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5k OCA], [http://pdbe.org/3q5k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q5k RCSB], [http://www.ebi.ac.uk/pdbsum/3q5k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5k OCA], [https://pdbe.org/3q5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5k RCSB], [https://www.ebi.ac.uk/pdbsum/3q5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5k ProSAT]</span></td></tr>
</table>
</table>
==See Also==
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Leima]]
[[Category: Leima]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith, C H]]

Revision as of 08:52, 8 June 2022

Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitorCrystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor

Structural highlights

3q5k is a 1 chain structure with sequence from Leima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:LMJF33.0312 (LEIMA)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

3q5k, resolution 2.35Å

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