3phu: Difference between revisions

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==OTU Domain of Crimean Congo Hemorrhagic Fever Virus==
==OTU Domain of Crimean Congo Hemorrhagic Fever Virus==
<StructureSection load='3phu' size='340' side='right' caption='[[3phu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3phu' size='340' side='right'caption='[[3phu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3phu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cchfi Cchfi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PHU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3phu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cchfi Cchfi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3phw|3phw]], [[3phx|3phx]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3phw|3phw]], [[3phx|3phx]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=652961 CCHFI])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=652961 CCHFI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3phu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phu OCA], [http://pdbe.org/3phu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3phu RCSB], [http://www.ebi.ac.uk/pdbsum/3phu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3phu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phu OCA], [https://pdbe.org/3phu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phu RCSB], [https://www.ebi.ac.uk/pdbsum/3phu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/L_CCHFI L_CCHFI]] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity.  
[[https://www.uniprot.org/uniprot/L_CCHFI L_CCHFI]] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity.  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Cchfi]]
[[Category: Cchfi]]
[[Category: Large Structures]]
[[Category: Akutsu, M]]
[[Category: Akutsu, M]]
[[Category: Komander, D]]
[[Category: Komander, D]]

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