3n0u: Difference between revisions
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==Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima== | ==Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima== | ||
<StructureSection load='3n0u' size='340' side='right' caption='[[3n0u]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='3n0u' size='340' side='right'caption='[[3n0u]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3n0u]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3n0u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N0U FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ogg, Tm1821, TM_1821 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ogg, Tm1821, TM_1821 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0u OCA], [https://pdbe.org/3n0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n0u RCSB], [https://www.ebi.ac.uk/pdbsum/3n0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n0u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/OGG1_THEMA OGG1_THEMA]] Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity). | ||
==See Also== | |||
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Atcc 43589]] | [[Category: Atcc 43589]] | ||
[[Category: Large Structures]] | |||
[[Category: Cooper, D R]] | [[Category: Cooper, D R]] | ||
[[Category: Derewenda, Z S]] | [[Category: Derewenda, Z S]] |