3jav: Difference between revisions
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<SX load='3jav' size='340' side='right' viewer='molstar' caption='[[3jav]], [[Resolution|resolution]] 4.70Å' scene=''> | <SX load='3jav' size='340' side='right' viewer='molstar' caption='[[3jav]], [[Resolution|resolution]] 4.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3jav]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3jav]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JAV FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jav OCA], [https://pdbe.org/3jav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jav RCSB], [https://www.ebi.ac.uk/pdbsum/3jav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jav ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ITPR1_RAT ITPR1_RAT]] Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == |