2xw1: Difference between revisions

<table><tr><td colspan='2'>[[2xw1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XW1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XW1 FirstGlance]. <br>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bxq|2bxq]], [[1hk4|1hk4]], [[2bxi|2bxi]], [[2xvu|2xvu]], [[2vuf|2vuf]], [[2xvv|2xvv]], [[1o9x|1o9x]], [[1bke|1bke]], [[2bxk|2bxk]], [[1hk1|1hk1]], [[1uor|1uor]], [[1h9z|1h9z]], [[1e7b|1e7b]], [[1hk2|1hk2]], [[1hk5|1hk5]], [[2esg|2esg]], [[1e7e|1e7e]], [[2xvq|2xvq]], [[2bxg|2bxg]], [[2bxh|2bxh]], [[2bxo|2bxo]], [[2bxf|2bxf]], [[1ysx|1ysx]], [[1e7g|1e7g]], [[1ao6|1ao6]], [[2bxc|2bxc]], [[1tf0|1tf0]], [[2bxn|2bxn]], [[2bxe|2bxe]], [[1e7c|1e7c]], [[1gnj|1gnj]], [[1e7h|1e7h]], [[2bxa|2bxa]], [[1hk3|1hk3]], [[2xvw|2xvw]], [[1e7i|1e7i]], [[2bxb|2bxb]], [[2bxl|2bxl]], [[1gni|1gni]], [[1ha2|1ha2]], [[1bj5|1bj5]], [[1e7a|1e7a]], [[2bxp|2bxp]], [[1bm0|1bm0]], [[2bxd|2bxd]], [[1e78|1e78]], [[2vdb|2vdb]], [[1e7f|1e7f]], [[1n5u|1n5u]], [[2bx8|2bx8]], [[2bxm|2bxm]], [[2vue|2vue]], [[2xw0|2xw0]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xw1 OCA], [http://pdbe.org/2xw1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2xw1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xw1 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>   

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>