1gye: Difference between revisions

Revision as of 18:10, 2 May 2008

STRUCTURE OF CELLVIBRIO CELLULOSA ALPHA-L-ARABINANASE COMPLEXED WITH ARABINOHEXAOSE

OverviewOverview

Cellvibrio japonicus arabinanase Arb43A hydrolyzes the alpha-1,5-linked L-arabinofuranoside backbone of plant cell wall arabinans. The three-dimensional structure of Arb43A, determined at 1.9 A resolution, reveals a five-bladed beta-propeller fold. Arb43A is the first enzyme known to display this topology. A long V-shaped surface groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. Three carboxylates deep in the active site groove provide the general acid and base components for glycosidic bond hydrolysis with inversion of anomeric configuration.

About this StructureAbout this Structure

1GYE is a Single protein structure of sequence from Cellvibrio japonicus. Full crystallographic information is available from OCA.

ReferenceReference

Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold., Nurizzo D, Turkenburg JP, Charnock SJ, Roberts SM, Dodson EJ, McKie VA, Taylor EJ, Gilbert HJ, Davies GJ, Nat Struct Biol. 2002 Sep;9(9):665-8. PMID:12198486 Page seeded by OCA on Fri May 2 18:10:35 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:1gye.jpg|left|200px]]
- {{Structure
+<!--
-|PDB= 1gye |SIZE=350|CAPTION= <scene name='initialview01'>1gye</scene>, resolution 2.50&Aring;
+The line below this paragraph, containing "STRUCTURE_1gye", creates the "Structure Box" on the page.
-|SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+B'>AC1</scene>
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=AHR:ALPHA-L-ARABINOFURANOSE'>AHR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Arabinan_endo-1,5-alpha-L-arabinosidase Arabinan endo-1,5-alpha-L-arabinosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.99 3.2.1.99] </span>
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_1gye|  PDB=1gye  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gye OCA], [http://www.ebi.ac.uk/pdbsum/1gye PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1gye RCSB]</span>
-}}
 '''STRUCTURE OF CELLVIBRIO CELLULOSA ALPHA-L-ARABINANASE COMPLEXED WITH ARABINOHEXAOSE'''
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 [[Category: Taylor, E J.]]
 [[Category: Turkenburg, J P.]]
-[[Category: arabinanase]]
+[[Category: Arabinanase]]
-[[Category: catalysis]]
+[[Category: Catalysis]]
-[[Category: cellvibrio]]
+[[Category: Cellvibrio]]
-[[Category: hydrolase]]
+[[Category: Hydrolase]]
-[[Category: propeller]]
+[[Category: Propeller]]
-[[Category: pseudomona]]
+[[Category: Pseudomona]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 18:10:35 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:54:00 2008''