User:Kia Yang/sandbox: Difference between revisions
New page: This page is being worked on during the Spring 2022 semester. ==Function== Methionine is an essential amino acid required by our bodies for healthy cell and tissue growth. It is essentia... |
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PDB ID: 1K7Y refers to the B12 domain of MS. | PDB ID: 1K7Y refers to the B12 domain of MS. | ||
[[Image: | [[Image:cob_1_alamin.jpeg]] | ||
In the Cob(I)alamin binding domain, the imidazole side chain containing His 759 replaces the dimethylbenzimidazole (DMB) ligand. His 759 then bonds to Asp 757 and See 810 via hydrogen bonds to create a ligand trifecta that increases the efficiency of the methyl transfer during the catalytic cycle<ref name="Bandarian et al"/>. | In the Cob(I)alamin binding domain, the imidazole side chain containing His 759 replaces the dimethylbenzimidazole (DMB) ligand. His 759 then bonds to Asp 757 and See 810 via hydrogen bonds to create a ligand trifecta that increases the efficiency of the methyl transfer during the catalytic cycle<ref name="Bandarian et al"/>. | ||