Notch signaling pathway: Difference between revisions

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New page: <StructureSection load='1pb5' size='340' side='right' caption='NMR Structure of a Prototype LNR Module from Human Notch1 (1pb5)' scene=''> This is a default text for your page '''Notch...
 
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<StructureSection load='1pb5' size='340' side='right' caption='NMR Structure of a Prototype LNR Module from Human Notch1 ([[1pb5]])' scene=''>
<StructureSection load='1pb5' size='340' side='right' caption='NMR Structure of a Prototype LNR Module from Human Notch1 ([[1pb5]])' scene=''>
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The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
 
== Function ==
 
== Disease ==
 
== Relevance ==
 
== Structural highlights ==
 
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


</StructureSection>
</StructureSection>
== References ==
== References ==
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Revision as of 12:26, 12 April 2022

The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region


NMR Structure of a Prototype LNR Module from Human Notch1 (1pb5)

Drag the structure with the mouse to rotate

ReferencesReferences

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