TGF beta signaling pathway: Difference between revisions
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==The TGF beta superfamily of ligands== | ==The TGF beta superfamily of ligands== | ||
<scene name='41/416407/Tgfbeta-1/1'> TGFβ Superfamily of cytokines</scene> | <scene name='41/416407/Tgfbeta-1/1'> TGFβ Superfamily of cytokines</scene> | ||
The TGFbeta superfamily of cytokines can be divided in two major ligand subfamilies by sequence similarities. On one hand TGFbeta/Inhibin/Nodal/Activin subfamily and on the other hand BMP (Bone Morphogenetic Protein)/AMH (Anti-Müllerian Hormone)/GDF (Growth and Differentiation Factor) subfamily. As shown here <scene name='41/416407/Tgfbeta-bmp7/1'>TgF beta in comparison with BMP-7</scene> , the members of the superfamily share a high conserved | The TGFbeta superfamily of cytokines can be divided in two major ligand subfamilies by sequence similarities. On one hand TGFbeta/Inhibin/Nodal/Activin subfamily and on the other hand BMP (Bone Morphogenetic Protein)/AMH (Anti-Müllerian Hormone)/GDF (Growth and Differentiation Factor) subfamily. As shown here <scene name='41/416407/Tgfbeta-bmp7/1'>TgF beta in comparison with BMP-7</scene> , the members of the superfamily share a high conserved 3D structure. | ||
''' TGFβ isoforms''': <scene name='41/416407/Dimer_tgf_beta/1'>TgF beta dimer</scene>. | |||
===Bone morphogenetic protein=== | ===Bone morphogenetic protein=== | ||
[[Bone morphogenetic protein]] | [[Bone morphogenetic protein]] | ||