Methionine synthase: Difference between revisions

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<StructureSection load='1k7y' size='310' side='right' caption='B-12 dependent fragment of E. coli methionine synthase with Cobalamin (in pink)' scene=''>
<StructureSection load='1k7y' size='310' side='right' caption='B-12 dependent fragment of E. coli methionine synthase with Cobalamin (in pink)' scene=''>
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</StructureSection>
</StructureSection>


[[Image:MetHsynthase.jpeg]]
[[Image:Overall.jpeg]]


The change from homocysteine to methionine is one methyl group, by which is received from methyltetrahydrofolate (MTHF), a product of Methylenetetrahydrofolate reductase (MTHFR), as the methyl donor and a protein-bound B-12 vitamin Cobalamin as the methyl carrier.
The change from homocysteine to methionine is one methyl group, by which is received from methyltetrahydrofolate (MTHF), a product of Methylenetetrahydrofolate reductase (MTHFR), as the methyl donor and a protein-bound B-12 vitamin Cobalamin as the methyl carrier.

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Kia Yang, Karsten Theis, Michael O'Shaughnessy, Anna Postnikova, Michal Harel