Hedgehog signaling pathway: Difference between revisions

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New page: <StructureSection load='6dmy' size='340' side='right' caption='Glycosylated human Ptch1 ectodomain 1 (salmon) complex with sonic hedgehog protein (deepskyblue), cholesterol derivative, Zn+...
 
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<StructureSection load='6dmy' size='340' side='right' caption='Glycosylated human Ptch1 ectodomain 1 (salmon) complex with sonic hedgehog protein (deepskyblue), cholesterol derivative, Zn+2 (grey) and Ca+2 (green) ions (PDB code [[6dmy]])' scene='87/874449/Cv/2'>
<StructureSection load='6dmy' size='340' side='right' caption='Glycosylated human Ptch1 ectodomain 1 (salmon) complex with sonic hedgehog protein (deepskyblue), cholesterol derivative, Zn+2 (grey) and Ca+2 (green) ions (PDB code [[6dmy]])' scene='87/874449/Cv/2'>
This is a default text for your page '''Hedgehog signaling pathway'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.


== Function ==
Mammals have three Hedgehog homologues, Desert (DHH), Indian (IHH), and Sonic (SHH), of which Sonic is the best studied. The pathway is equally important during vertebrate embryonic development and is therefore of interest in evolutionary developmental biology.
 
== Disease ==
 
== Relevance ==
 
== Structural highlights ==
 
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


</StructureSection>
</StructureSection>
== References ==
== References ==
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<references/>

Revision as of 15:40, 31 March 2022

The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation.

Mammals have three Hedgehog homologues, Desert (DHH), Indian (IHH), and Sonic (SHH), of which Sonic is the best studied. The pathway is equally important during vertebrate embryonic development and is therefore of interest in evolutionary developmental biology.


Glycosylated human Ptch1 ectodomain 1 (salmon) complex with sonic hedgehog protein (deepskyblue), cholesterol derivative, Zn+2 (grey) and Ca+2 (green) ions (PDB code 6dmy)

Drag the structure with the mouse to rotate

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky
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