2vdu: Difference between revisions

<table><tr><td colspan='2'>[[2vdu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VDU FirstGlance]. <br>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vdv|2vdv]]</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(46)-N(7))-methyltransferase tRNA (guanine(46)-N(7))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.33 2.1.1.33] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vdu OCA], [http://pdbe.org/2vdu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vdu RCSB], [http://www.ebi.ac.uk/pdbsum/2vdu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vdu ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/TRM82_YEAST TRM82_YEAST]] Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.<ref>PMID:15811913</ref> <ref>PMID:16387656</ref> <ref>PMID:17382321</ref> <ref>PMID:18184583</ref>  [[http://www.uniprot.org/uniprot/TRMB_YEAST TRMB_YEAST]] Methyltransferase that catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay. Both the D-stem and T-stem structures of tRNAs are required for efficient methyltransferase activity.[HAMAP-Rule:MF_03055]<ref>PMID:16387656</ref> <ref>PMID:17382321</ref>