2v24: Difference between revisions

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<StructureSection load='2v24' size='340' side='right'caption='[[2v24]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2v24' size='340' side='right'caption='[[2v24]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2v24]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V24 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2V24 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2v24]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V24 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2v24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v24 OCA], [http://pdbe.org/2v24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v24 RCSB], [http://www.ebi.ac.uk/pdbsum/2v24 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v24 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v24 OCA], [https://pdbe.org/2v24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v24 RCSB], [https://www.ebi.ac.uk/pdbsum/2v24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v24 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SPSB4_HUMAN SPSB4_HUMAN]] Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<ref>PMID:15601820</ref>   
[[https://www.uniprot.org/uniprot/SPSB4_HUMAN SPSB4_HUMAN]] Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<ref>PMID:15601820</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

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