Semaphorin: Difference between revisions

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== Structural insights ==
== Structural insights ==
SEMA interacts with plexin C1 via 3 regions: <scene name='46/466531/Cv/5'>SEMA extrusion helix</scene>, <scene name='46/466531/Cv/6'>loop4c-4d</scene> and <scene name='46/466531/Cv/7'>blade 3</scene><ref>PMID:20727575</ref>. Water molecules are shown as red spheres.
SEMA interacts with plexin C1 via 3 regions: <scene name='46/466531/Cv/5'>SEMA extrusion helix</scene>, <scene name='46/466531/Cv/6'>loop4c-4d</scene> and <scene name='46/466531/Cv/7'>blade 3</scene><ref>PMID:20727575</ref>. Water molecules are shown as red spheres.
</StructureSection>
 
==3D structures of semaphorin==
==3D structures of semaphorin==


[[Semaphorin 3D structures]]
[[Semaphorin 3D structures]]


{{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
</StructureSection>
{{#tree:id=OrganizedByTopic|openlevels=0|
 
*Semaphorin 1A
 
**[[6qp9]] – DmSEMA 1A  domain 1-2 – ''Drosophila melanogaster''<br />
 
*Semaphorin 1B
 
**[[6fkk]] – DmSEMA 1B extracellular domains 37-602<br />
**[[6fkm]], [[6fkn]] – DmSEMA 1B extracellular domains + plexin A<br />
 
*Semaphorin 2A
 
**[[6qp7]] – DmSEMA 2A <br />
 
*Semaphorin 2B
 
**[[6qp8]] – DmSEMA 2B <br />
 
*Semaphorin 3A
 
**[[1q47]], [[4gz8]] – mSEMA 3A – mouse<br />
**[[4gza]] – mSEMA 3A + plexin A2 + neuropilin 1<br />
**[[7m0r]] – mSEMA 3A + plexin A4 + neuropilin 1 – Cryo EM<br />
 
*Semaphorin 4
 
**[[1olz]] – hSEMA 4D extracellular domain – human
 
**[[3ol2]] - hSEMA 4D extracellular domain + plexin-B1
 
*Semaphorin 6A
 
**[[6wts]] – hSEMA 6A + cytotoxin L <br />
**[[3afc]], [[3okw]] - mSEMA 6A extracellular domain
 
**[[3al8]], [[3oky]] - mSEMA 6A + plexin-A2
 
*Semaphorin 7
 
**[[3nvn]], [[3nvq]], [[3nvx]] – hSEMA 7A + plexin-C1
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky