3fdw: Difference between revisions

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==Crystal structure of a C2 domain from human synaptotagmin-like protein 4==
==Crystal structure of a C2 domain from human synaptotagmin-like protein 4==
<StructureSection load='3fdw' size='340' side='right' caption='[[3fdw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3fdw' size='340' side='right'caption='[[3fdw]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fdw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FDW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FDW FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FDW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FDW FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SYTL4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fdw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fdw OCA], [https://pdbe.org/3fdw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fdw RCSB], [https://www.ebi.ac.uk/pdbsum/3fdw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fdw ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3fdw TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fdw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fdw OCA], [http://pdbe.org/3fdw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fdw RCSB], [http://www.ebi.ac.uk/pdbsum/3fdw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fdw ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3fdw TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/SYTL4_HUMAN SYTL4_HUMAN]] Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fd/3fdw_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fd/3fdw_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
Line 19: Line 16:
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fdw ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fdw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Exophilin 3D structures|Exophilin 3D structures]]
*[[Synaptotagmin 3D structures|Synaptotagmin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Bain, K T]]
[[Category: Bain KT]]
[[Category: Bonanno, J B]]
[[Category: Bonanno JB]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Miller, S]]
[[Category: Miller S]]
[[Category: Structural genomic]]
[[Category: Romero R]]
[[Category: Romero, R]]
[[Category: Rutter M]]
[[Category: Rutter, M]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Wasserman S]]
[[Category: Wasserman, S]]
[[Category: Alternative splicing]]
[[Category: Cell membrane]]
[[Category: Cytoplasmic vesicle]]
[[Category: Lipid binding protein]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Phospholipid binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: PSI, Protein structure initiative]]
[[Category: Zinc]]
[[Category: Zinc-finger]]

Revision as of 10:58, 2 March 2022

Crystal structure of a C2 domain from human synaptotagmin-like protein 4Crystal structure of a C2 domain from human synaptotagmin-like protein 4

Structural highlights

Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

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