3fb2: Difference between revisions

<StructureSection load='3fb2' size='340' side='right' caption='[[3fb2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>

<table><tr><td colspan='2'>[[3fb2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FB2 FirstGlance]. <br>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u5p|1u5p]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPTA2, SPTAN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fb2 OCA], [http://pdbe.org/3fb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fb2 RCSB], [http://www.ebi.ac.uk/pdbsum/3fb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fb2 ProSAT], [http://www.topsan.org/Proteins/NESGC/3fb2 TOPSAN]</span></td></tr>

[[http://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN]] West syndrome. The disease is caused by mutations affecting the gene represented in this entry.  

[[http://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN]] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.