1v87: Difference between revisions

<table><tr><td colspan='2'>[[1v87]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V87 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1V87 FirstGlance]. <br>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610524D08 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1v87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v87 OCA], [http://pdbe.org/1v87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v87 RCSB], [http://www.ebi.ac.uk/pdbsum/1v87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1v87 ProSAT], [http://www.topsan.org/Proteins/RSGI/1v87 TOPSAN]</span></td></tr>

[[http://www.uniprot.org/uniprot/DTX2_MOUSE DTX2_MOUSE]] Recurrent site of retroviral integration in murine B-cell lymphomas.  

[[http://www.uniprot.org/uniprot/DTX2_MOUSE DTX2_MOUSE]] Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity).