MAPK/ERK pathway: Difference between revisions

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====MAPK can phosphorylate [[C-myc]]====
====MAPK can phosphorylate [[C-myc]]====


====MAPK phosphorylates and activates MNK, which, in turn, phosphorylates CREB. [[CREB-binding protein]]. The activated CREB protein then binds to a CRE region, and is then bound to by CBP ([[CREB-binding protein]]), which coactivates it, allowing it to switch certain genes on or off. CBP is a transcription activator.====
====MAPK phosphorylates and activates MNK, which, in turn, phosphorylates CREB. The activated CREB protein then binds to a CRE region, and is then bound to by CBP ([[CREB-binding protein]]), which coactivates it, allowing it to switch certain genes on or off. CBP is a transcription activator.====


</StructureSection>
</StructureSection>
== References ==
== References ==
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