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==Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804== | ==Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804== | ||
<StructureSection load='3eb0' size='340' side='right' caption='[[3eb0]], [[Resolution|resolution]] 2.65Å' scene=''> | <StructureSection load='3eb0' size='340' side='right'caption='[[3eb0]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3eb0]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3eb0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EB0 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DRK:3-({[(3S)-3,4-DIHYDROXYBUTYL]OXY}AMINO)-1H,2H-2,3-BIINDOL-2-ONE'>DRK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DRK:3-({[(3S)-3,4-DIHYDROXYBUTYL]OXY}AMINO)-1H,2H-2,3-BIINDOL-2-ONE'>DRK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cgd4_240 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cgd4_240 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb0 OCA], [https://pdbe.org/3eb0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eb0 RCSB], [https://www.ebi.ac.uk/pdbsum/3eb0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eb0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb0_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb0_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Crypi]] | [[Category: Crypi]] | ||
[[Category: Large Structures]] | |||
[[Category: Ali, A]] | [[Category: Ali, A]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] |
Revision as of 14:45, 16 February 2022
Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804
Structural highlights
Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Crypi
- Large Structures
- Ali, A
- Arrowsmith, C H
- Bochkarev, A
- Bountra, C
- Edwards, A M
- Fedorov, O
- Hui, R
- Kozieradzki, I
- Lam, A
- Lew, J
- Lin, Y H
- Structural genomic
- Schapira, M
- Vedadi, M
- Wasney, G
- Wernimont, A K
- Wilstrom, M
- Zhao, Y
- Atp-binding
- Kinase
- Kinase cryptosporidium parvum
- Nucleotide-binding
- Serine/threonine-protein kinase
- Sgc
- Transferase
- Unknown function