COVID-19 AlphaFold2 Models: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman

Revision as of 18:47, 4 February 2022 view source Joel L. Sussman (talk \| contribs) ConfirmAccount, Editor, Journal, Mutation, Print3D, Tester, Bureaucrats, Administrators 7,920 edits No edit summary ← Older edit		Revision as of 18:48, 4 February 2022 view source Joel L. Sussman (talk \| contribs) ConfirmAccount, Editor, Journal, Mutation, Print3D, Tester, Bureaucrats, Administrators 7,920 edits No edit summary Newer edit →
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	At present, there a still a number of proteins from the SARS CoV-2 virus whose 3D structures have not yet been experimentally determined. [[AlphaFold]]2 was used to predict these structures using the MIT ColabFold server<ref name="MIT_ColabFold"> MIT ColabFold https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb </ref>. For each prediction, five 3D models were predicted, ranked from 1 to 5 (with 1 being the best). Views of these AlphaFold2 predictions can be seen on the Proteopedia pages:<br>		At present, there a still a number of proteins from the SARS CoV-2 virus whose 3D structures have not yet been experimentally determined. [[AlphaFold]]2 was used to predict these structures using the MIT ColabFold server<ref name="MIT_ColabFold"> MIT ColabFold https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb </ref>. For each prediction, five 3D models were predicted, ranked from 1 to 5 (with 1 being the best). Views of these AlphaFold2 predictions can be seen on the Proteopedia pages:<br>


	'''[[SARS-CoV-2 protein M]]''' - Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins<ref name="Zhang Lab"> Modeling of the SARS-COV-2 Genome https://zhanglab.ccmb.med.umich.edu/COVID-19/</ref><ref name="Zhang"> pmid 32200634</ref>.		'''[[SARS-CoV-2 protein M]]''' - Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins<ref name="Zhang Lab"> Modeling of the SARS-COV-2 Genome https://zhanglab.ccmb.med.umich.edu/COVID-19/</ref><ref name="Zhang"> pmid 32200634</ref>.