3d3m: Difference between revisions

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==The Crystal Structure of the C-terminal region of Death Associated Protein 5(DAP5)==
==The Crystal Structure of the C-terminal region of Death Associated Protein 5(DAP5)==
<StructureSection load='3d3m' size='340' side='right' caption='[[3d3m]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3d3m' size='340' side='right'caption='[[3d3m]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3d3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D3M FirstGlance]. <br>
<table><tr><td colspan='2'>[[3d3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D3M FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EIF4G2, DAP5, OK/SW-cl.75 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EIF4G2, DAP5, OK/SW-cl.75 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3m OCA], [http://pdbe.org/3d3m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d3m RCSB], [http://www.ebi.ac.uk/pdbsum/3d3m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3m OCA], [https://pdbe.org/3d3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d3m RCSB], [https://www.ebi.ac.uk/pdbsum/3d3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IF4G2_HUMAN IF4G2_HUMAN]] Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.<ref>PMID:9049310</ref> <ref>PMID:9032289</ref> <ref>PMID:11511540</ref> <ref>PMID:11943866</ref>   
[[https://www.uniprot.org/uniprot/IF4G2_HUMAN IF4G2_HUMAN]] Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.<ref>PMID:9049310</ref> <ref>PMID:9032289</ref> <ref>PMID:11511540</ref> <ref>PMID:11943866</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[C-terminal portion of human eIF4GI|C-terminal portion of human eIF4GI]]
*[[Death Associated Protein 5|Death Associated Protein 5]]
*[[Death-associated protein|Death-associated protein]]
*[[Death-associated protein|Death-associated protein]]
*[[Eukaryotic initiation factor|Eukaryotic initiation factor]]
*[[Death-associated protein 3D structures|Death-associated protein 3D structures]]
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Dym, O]]
[[Category: Dym, O]]
[[Category: ISPC, Israel Structural Proteomics Center]]
[[Category: ISPC, Israel Structural Proteomics Center]]

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