3d3m: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==The Crystal Structure of the C-terminal region of Death Associated Protein 5(DAP5)== | ==The Crystal Structure of the C-terminal region of Death Associated Protein 5(DAP5)== | ||
<StructureSection load='3d3m' size='340' side='right' caption='[[3d3m]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='3d3m' size='340' side='right'caption='[[3d3m]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3d3m]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3d3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D3M FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EIF4G2, DAP5, OK/SW-cl.75 ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EIF4G2, DAP5, OK/SW-cl.75 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3m OCA], [https://pdbe.org/3d3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d3m RCSB], [https://www.ebi.ac.uk/pdbsum/3d3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/IF4G2_HUMAN IF4G2_HUMAN]] Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.<ref>PMID:9049310</ref> <ref>PMID:9032289</ref> <ref>PMID:11511540</ref> <ref>PMID:11943866</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 30: | Line 30: | ||
==See Also== | ==See Also== | ||
*[[Death-associated protein|Death-associated protein]] | *[[Death-associated protein|Death-associated protein]] | ||
*[[Eukaryotic initiation factor|Eukaryotic initiation factor]] | *[[Death-associated protein 3D structures|Death-associated protein 3D structures]] | ||
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
Line 39: | Line 38: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Dym, O]] | [[Category: Dym, O]] | ||
[[Category: ISPC, Israel Structural Proteomics Center]] | [[Category: ISPC, Israel Structural Proteomics Center]] |