3ca7: Difference between revisions

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==High Resolution Crystal Structure of the EGF domain of Spitz==
==High Resolution Crystal Structure of the EGF domain of Spitz==
<StructureSection load='3ca7' size='340' side='right' caption='[[3ca7]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3ca7' size='340' side='right'caption='[[3ca7]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ca7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CA7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CA7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ca7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CA7 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spi ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ca7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ca7 OCA], [http://pdbe.org/3ca7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ca7 RCSB], [http://www.ebi.ac.uk/pdbsum/3ca7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ca7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ca7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ca7 OCA], [https://pdbe.org/3ca7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ca7 RCSB], [https://www.ebi.ac.uk/pdbsum/3ca7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ca7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SPITZ_DROME SPITZ_DROME]] Ligand for the EGF receptor (Gurken). Involved in a number of unrelated developmental choices, for example, dorsal-ventral axis formation, glial migration, sensory organ determination, and muscle development. It is required for photoreceptor determination.<ref>PMID:7833286</ref>   
[[https://www.uniprot.org/uniprot/SPITZ_DROME SPITZ_DROME]] Ligand for the EGF receptor (Gurken). Involved in a number of unrelated developmental choices, for example, dorsal-ventral axis formation, glial migration, sensory organ determination, and muscle development. It is required for photoreceptor determination.<ref>PMID:7833286</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Klein, D E]]
[[Category: Klein, D E]]
[[Category: Lemmon, M A]]
[[Category: Lemmon, M A]]

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