Pyrrolysine: Difference between revisions
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Pyrrolysine is a naturally-occurring, genetically encoded [[Amino Acids|amino acid]], sometimes called the "22nd amino acid". For more information, please see [http://en.wikipedia.org/wiki/Pyrrolysine Pyrrolysine in Wikipedia]. | Pyrrolysine is a naturally-occurring, genetically encoded [[Amino Acids|amino acid]], sometimes called the "22nd amino acid". Its 3-letter code is '''PYL''' and its single letter code is '''O'''. For more information, please see [http://en.wikipedia.org/wiki/Pyrrolysine Pyrrolysine in Wikipedia]. | ||
==Occurrence== | ==Occurrence== | ||
In January, 2022, | In January, 2022, seven [[wwPDB]] entries contain PYL. (Prior to remediation, pyrrolysine was sometimes designated BGX or PYH. Those IDs are no longer in use in January, 2022.) | ||
Some proteins in methanogenic archaea include | Some proteins in methanogenic archaea include pyrrolysine. ''Methanosarcina barkeri'' monomethylamine methyltransferase (MtmB, [[1nth]], [[1l2q]]) was the first identified structure containing this amino acid<ref>PMID: 12029132</ref>. Chemically modified forms of pyrrolysine are present in the MtmB structures [[1tv2]], [[1tv3]], and [[1tv4]]<ref>PMID: 15380192</ref>. The [[wwPDB]] also contains several structures for pyrrolysyl-tRNA synthetase, including [[2zce]] which includes pyrrolysine. | ||
==References== | ==References== | ||
<references /> | <references /> | ||