Crystallin: Difference between revisions
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'''Crystallin''' is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. α-, β-, γ-, δ-crystallin are named according to the order they are eluted by gel filtration. δ-crystallin is found in avian and reptilian lenses.<ref>PMID:12729747</ref> | '''Crystallin''' is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. α-, β-, γ-, δ-crystallin are named according to the order they are eluted by gel filtration. δ-crystallin is found in avian and reptilian lenses.<ref>PMID:12729747</ref> | ||
See [[Alpha crystallin]]. | |||
== Disease == | == Disease == | ||
Revision as of 13:53, 16 January 2022
FunctionCrystallin is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. α-, β-, γ-, δ-crystallin are named according to the order they are eluted by gel filtration. δ-crystallin is found in avian and reptilian lenses.[1] See Alpha crystallin. DiseaseSeveral human cataracts have been linked to mutations in γ-D-crystallin[2]. 3D Structures of Crystallin
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ReferencesReferences
- ↑ Basak A, Bateman O, Slingsby C, Pande A, Asherie N, Ogun O, Benedek GB, Pande J. High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract. J Mol Biol. 2003 May 16;328(5):1137-47. PMID:12729747
- ↑ Pande A, Pande J, Asherie N, Lomakin A, Ogun O, King J, Benedek GB. Crystal cataracts: human genetic cataract caused by protein crystallization. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6116-20. PMID:11371638 doi:http://dx.doi.org/10.1073/pnas.101124798