Abundant perithecial protein: Difference between revisions
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==Abundant Perithecial Protein (APP) and Structural highlights == | ==Abundant Perithecial Protein (APP) and Structural highlights == | ||
<StructureSection load='5Z6D' size='340' side='right' caption='Abundant | <StructureSection load='5Z6D' size='340' side='right' caption='Abundant perithecial protein (PDB code [[5z6d]])' scene=''> | ||
'''Abundant Perithecial Protein''' (APP) consists of a <scene name='88/881546/Beta_gamma_crystallin/7'>Beta Gamma Crystallin</scene> domain, containing an [https://en.wikipedia.org/wiki/Immunoglobulin_domain Ig-like domain] and is commonly found in perithecia structures found in plants and fungi, where it resembles photosynthetic processes. APP is deficient in one Ca2+ binding property, similar to its homolog DdCAD-1, a calcium-binding cell-adhesion molecule. Because APP has dispensed it’s Ca2+ binding properties in exchange for increased stability, researchers are led to believe that APP is an ancestor of ocular crystallins due to its native crystallin-like attributes. Both 5Z6D and 5Z6E play key roles in cell adhesion. APP has been identified in [https://en.wikipedia.org/wiki/Neurospora_crassa neurospora crassa], Sordaria macrospora, two other members of Xylariales, and one species of aspergillus. APP is mostly found in fungi, maintaining high levels of sequence variance. | '''Abundant Perithecial Protein''' (APP) consists of a <scene name='88/881546/Beta_gamma_crystallin/7'>Beta Gamma Crystallin</scene> domain, containing an [https://en.wikipedia.org/wiki/Immunoglobulin_domain Ig-like domain] and is commonly found in perithecia structures found in plants and fungi, where it resembles photosynthetic processes. APP is deficient in one Ca2+ binding property, similar to its homolog DdCAD-1, a calcium-binding cell-adhesion molecule. Because APP has dispensed it’s Ca2+ binding properties in exchange for increased stability, researchers are led to believe that APP is an ancestor of ocular crystallins due to its native crystallin-like attributes. Both 5Z6D and 5Z6E play key roles in cell adhesion. APP has been identified in [https://en.wikipedia.org/wiki/Neurospora_crassa neurospora crassa], Sordaria macrospora, two other members of Xylariales, and one species of aspergillus. APP is mostly found in fungi, maintaining high levels of sequence variance. | ||