Neuropeptides: Difference between revisions
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There are over 100 known neuropeptides, representing the largest and most diverse class of signaling molecules in the nervous system. Neuropeptides are synthesized from large precursor proteins which are cleaved and post-translationally processed then packaged into dense core vesicles. Neuropeptides are often co-released with other neuropeptides and neurotransmitters in a single neuron, yielding a multitude of effects. Once released, neuropeptides can diffuse widely to affect a broad range of targets. | There are over 100 known neuropeptides, representing the largest and most diverse class of signaling molecules in the nervous system. Neuropeptides are synthesized from large precursor proteins which are cleaved and post-translationally processed then packaged into dense core vesicles. Neuropeptides are often co-released with other neuropeptides and neurotransmitters in a single neuron, yielding a multitude of effects. Once released, neuropeptides can diffuse widely to affect a broad range of targets. | ||
Neuropeptides are often co-released with other neurotransmitters and neuropeptides to modulate synaptic activity. | Neuropeptides are often co-released with other neurotransmitters and neuropeptides to modulate synaptic activity. Norepinephrine (noradrenaline). In neurons of the A2 cell group in the nucleus of the solitary tract), norepinephrine co-exists with neuropeptides Galanin, Enkephalin, Neuropeptide Y. | ||
<scene name='90/900769/Cv/6'>Oxytocin</scene> (from PDB entry [[7otd]]) and <scene name='90/900769/Cv/4'>vasopressin</scene> (from PDB entry [[7bb7]]) have striking and specific effects on social behaviours, including maternal behaviour and pair bonding. | <scene name='90/900769/Cv/6'>Oxytocin</scene> (from PDB entry [[7otd]]) and <scene name='90/900769/Cv/4'>vasopressin</scene> (from PDB entry [[7bb7]]) have striking and specific effects on social behaviours, including maternal behaviour and pair bonding. |