1g1x: Difference between revisions

Revision as of 17:01, 2 May 2008

STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA

OverviewOverview

The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a 104-nucleotide RNA fragment composed of two three-helix junctions that lie at the end of a central helix, and the ribosomal proteins S15, S6, and S18. S15 binds the ribosomal RNA early in the assembly of the 30S ribosomal subunit, stabilizing a conformational reorganization of the two three-helix junctions that creates the RNA fold necessary for subsequent binding of S6 and S18. The structure of the complex demonstrates the central role of S15-induced reorganization of central domain RNA for the subsequent steps of ribosome assembly.

About this StructureAbout this Structure

1G1X is a Protein complex structure of sequences from Thermus thermophilus. This structure supersedes the now removed PDB entry 1ekc. Full crystallographic information is available from OCA.

ReferenceReference

Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:10753109 Page seeded by OCA on Fri May 2 17:01:54 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:1g1x.gif|left|200px]]
- {{Structure
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 '''STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA'''
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 ==About this Structure==
-G1X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry 1EKC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA].
+G1X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekc 1ekc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA].
 ==Reference==
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 [[Category: Stout, C D.]]
 [[Category: Williamson, J R.]]
-[[Category: ribosomal proteins s15]]
+[[Category: Ribosomal proteins s15]]
-[[Category: ribosome]]
+[[Category: Ribosome]]
-[[Category: rna]]
+[[Category: Rna]]
-[[Category: s18]]
+[[Category: S18]]
-[[Category: s30 ribosomal subunit]]
+[[Category: S30 ribosomal subunit]]
-[[Category: s6]]
+[[Category: S6]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 17:01:54 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:34:54 2008''