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==Structural and biochemical characterization of ClfB:ligand interactions== | ==Structural and biochemical characterization of ClfB:ligand interactions== | ||
<StructureSection load='3asw' size='340' side='right' caption='[[3asw]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='3asw' size='340' side='right'caption='[[3asw]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3asw]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3asw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staan Staan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ASW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ASW FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3at0|3at0]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3at0|3at0]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">clfB, SA2423 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">clfB, SA2423 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158879 STAAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3asw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3asw OCA], [https://pdbe.org/3asw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3asw RCSB], [https://www.ebi.ac.uk/pdbsum/3asw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3asw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[[ | [[https://www.uniprot.org/uniprot/K1C10_HUMAN K1C10_HUMAN]] Congenital reticular ichthyosiform erythroderma;Annular epidermolytic ichthyosis;Epidermolytic ichthyosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/CLFB_STAAN CLFB_STAAN]] Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps (By similarity). | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Staan]] | [[Category: Staan]] | ||
[[Category: Ganesh, V K]] | [[Category: Ganesh, V K]] |
Revision as of 18:03, 29 December 2021
Structural and biochemical characterization of ClfB:ligand interactionsStructural and biochemical characterization of ClfB:ligand interactions
Structural highlights
Disease[K1C10_HUMAN] Congenital reticular ichthyosiform erythroderma;Annular epidermolytic ichthyosis;Epidermolytic ichthyosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Function[CLFB_STAAN] Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps (By similarity). See Also |
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