2yki: Difference between revisions

<table><tr><td colspan='2'>[[2yki]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YKI FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=YKI:1-H-PYRROLO[2,3-B]PYRIDINE-4-CARBOXYLIC+ACID+[4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-9H-FLUOREN-9-YL]-AMIDE'>YKI</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yk9|2yk9]], [[2yi0|2yi0]], [[1osf|1osf]], [[2bsm|2bsm]], [[2wi3|2wi3]], [[2ye4|2ye4]], [[2yi5|2yi5]], [[2ye5|2ye5]], [[2bz5|2bz5]], [[2yei|2yei]], [[2ccs|2ccs]], [[2yeg|2yeg]], [[1yc3|1yc3]], [[1uyf|1uyf]], [[1uyi|1uyi]], [[2ye3|2ye3]], [[2byi|2byi]], [[2yi6|2yi6]], [[2vci|2vci]], [[2wi1|2wi1]], [[2xjx|2xjx]], [[2fwz|2fwz]], [[2xdk|2xdk]], [[1uyh|1uyh]], [[2xjg|2xjg]], [[2fwy|2fwy]], [[1uyl|1uyl]], [[1uye|1uye]], [[2xab|2xab]], [[2yeh|2yeh]], [[2xht|2xht]], [[2xhr|2xhr]], [[1uy7|1uy7]], [[2yef|2yef]], [[2byh|2byh]], [[2wi5|2wi5]], [[1yes|1yes]], [[1uy9|1uy9]], [[2cdd|2cdd]], [[1byq|1byq]], [[2yi7|2yi7]], [[1uy8|1uy8]], [[2bug|2bug]], [[2wi4|2wi4]], [[2yeb|2yeb]], [[2uwd|2uwd]], [[2ye7|2ye7]], [[2ykc|2ykc]], [[2wi7|2wi7]], [[2xhx|2xhx]], [[2bt0|2bt0]], [[2yej|2yej]], [[1yer|1yer]], [[2yec|2yec]], [[2xdu|2xdu]], [[1uyg|1uyg]], [[2ccu|2ccu]], [[2xds|2xds]], [[2xdx|2xdx]], [[2xk2|2xk2]], [[2xjj|2xjj]], [[1uyd|1uyd]], [[2xdl|2xdl]], [[2wi2|2wi2]], [[2yee|2yee]], [[1uy6|1uy6]], [[2ye2|2ye2]], [[2vcj|2vcj]], [[1yc4|1yc4]], [[2ye9|2ye9]], [[2c2l|2c2l]], [[1uyk|1uyk]], [[2cct|2cct]], [[2yk2|2yk2]], [[2wi6|2wi6]], [[2yea|2yea]], [[1yc1|1yc1]], [[2ye6|2ye6]], [[2yed|2yed]], [[1uyc|1uyc]], [[1yet|1yet]], [[2yjx|2yjx]], [[2jjc|2jjc]], [[2ye8|2ye8]], [[2ykb|2ykb]], [[2ykj|2ykj]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yki OCA], [http://pdbe.org/2yki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yki RCSB], [http://www.ebi.ac.uk/pdbsum/2yki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yki ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>