2zpy: Difference between revisions
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==Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide== | ==Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide== | ||
<StructureSection load='2zpy' size='340' side='right' caption='[[2zpy]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2zpy' size='340' side='right'caption='[[2zpy]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2zpy]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2zpy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZPY FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gc7|1gc7]], [[1j19|1j19]], [[2yvc|2yvc]], [[2ems|2ems]], [[2emt|2emt]], [[2d2q|2d2q]], [[1gc6|1gc6]], [[2d10|2d10]], [[2d11|2d11]], [[1isn|1isn]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gc7|1gc7]], [[1j19|1j19]], [[2yvc|2yvc]], [[2ems|2ems]], [[2emt|2emt]], [[2d2q|2d2q]], [[1gc6|1gc6]], [[2d10|2d10]], [[2d11|2d11]], [[1isn|1isn]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rdx ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rdx ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpy OCA], [https://pdbe.org/2zpy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zpy RCSB], [https://www.ebi.ac.uk/pdbsum/2zpy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/RADI_MOUSE RADI_MOUSE]] Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane. [[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE]] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Fukami, Y]] | [[Category: Fukami, Y]] |