Protein Kinases: Difference between revisions

New page: <StructureSection load='' size='350' side='right' scene='48/483859/Cv/1' caption='Human Fyn tyrosine kinase kinase domain with phosphotyrosine in stick model complex with inhibitor stauros...
 
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<StructureSection load='' size='350' side='right' scene='48/483859/Cv/1' caption='Human Fyn tyrosine kinase kinase domain with phosphotyrosine in stick model complex with inhibitor staurosporine (PDB code [[2dq7]]).' pspeed='8'>
<StructureSection load='' size='350' side='right' scene='48/483859/Cv/1' caption='Human Fyn tyrosine kinase kinase domain with phosphotyrosine in stick model complex with inhibitor staurosporine (PDB code [[2dq7]]).' pspeed='8'>
This is a default text for your page '''Protein Kinases'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
*[[Calcium-dependent protein kinase]]
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
*[[Calcium/Calmodulin-dependent protein kinase]]
*[[Eukaryotic Protein Kinase Catalytic Domain]]
*[[Interleukin-1 receptor-associated kinase]]


== Function ==
''Tyrosine kinase''
*[[Receptor tyrosine kinases]]
*[[Tyrosine kinase]]
*[[Janus kinase]] or tyrosine-protein kinase JAK (JAK) are nonreceptor tyrosine kinases which transduces cytokine-mediated signals via the JAK-STAT pathway. The JAK-STAT pathway transmits signals through the cell membrane to DNA promoters thus causing transcription.


== Disease ==
''Protein kinase C''
*[[Protein kinase C]]
*The sensitization of [[TRPV1]] is thought to be connected to phosphorylation by [[protein kinase C]] and the cleavage of PIP2.


== Relevance ==
''MAPK''
*[[Mitogen-activated protein kinase]]
*[[Mitogen-activated protein kinase kinase]]
*[[Mitogen-activated protein kinase kinase kinase]]
*[[Michael Roberts/BIOL115/ERK2]]
*[[UMass Chem 423 Student Projects 2011-2#p38 kinase|p38 MAPK (UMass Chem 423 Student Projects 2011-2)]]


== Structural highlights ==


This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
 
''CAMP-dependent protein kinase''
*[[CAMP-dependent protein kinase]]
*[[CAMP Dependent Protein Kinase, Catalytic Subunit]]
*[[Protein Kinase A]]


</StructureSection>
</StructureSection>
== References ==
== References ==
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<references/>

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky