6tfl: Difference between revisions

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 ==Lsm protein (SmAP) from Halobacterium salinarum==
-<StructureSection load='6tfl' size='340' side='right'caption='[[6tfl]]' scene=''>
+<StructureSection load='6tfl' size='340' side='right'caption='[[6tfl]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TFL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TFL FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6tfl]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Hals3 Hals3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TFL FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tfl OCA], [http://pdbe.org/6tfl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tfl RCSB], [http://www.ebi.ac.uk/pdbsum/6tfl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tfl ProSAT]</span></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=URI:URIDINE'>URI</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ljo|1ljo]]</div></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lsm, snp, OE_3142R ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=478009 HALS3])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tfl OCA], [https://pdbe.org/6tfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tfl RCSB], [https://www.ebi.ac.uk/pdbsum/6tfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tfl ProSAT]</span></td></tr>
 </table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The structure and the RNA-binding properties of the Lsm protein from Halobacterium salinarum have been determined. A distinctive feature of this protein is the presence of a short L4 loop connecting the beta3 and beta4 strands. Since bacterial Lsm proteins (also called Hfq proteins) have a short L4 loop and form hexamers, whereas archaeal Lsm proteins (SmAP) have a long L4 loop and form heptamers, it has been suggested that the length of the L4 loop may affect the quaternary structure of Lsm proteins. Moreover, the L4 loop covers the region of SmAP corresponding to one of the RNA-binding sites in Hfq, and thus can affect the RNA-binding properties of the protein. Our results show that the SmAP from H. salinarum forms heptamers and possesses the same RNA-binding properties as homologous proteins with the long L4 loop. Therefore, the length of the L4 does not govern the number of monomers in the protein particles and does not affect the RNA-binding properties of Lsm proteins.
+Structure and RNA-Binding Properties of Lsm Protein from Halobacterium salinarum.,Fando MS, Mikhaylina AO, Lekontseva NV, Tishchenko SV, Nikulin AD Biochemistry (Mosc). 2021 Jul;86(7):833-842. doi: 10.1134/S000629792107004X. PMID:34284708<ref>PMID:34284708</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 6tfl" style="background-color:#fffaf0;"></div>
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Hals3]]
 [[Category: Large Structures]]
-[[Category: Fando MS]]
+[[Category: Fando, M S]]
-[[Category: Lekontseva NV]]
+[[Category: Lekontseva, N V]]
-[[Category: Nikulin AD]]
+[[Category: Nikulin, A D]]
+[[Category: Lsm]]
+[[Category: Rna binding protein]]
+[[Category: Rna-chaperon]]
+[[Category: Smap]]