2cu0: Difference between revisions

<table><tr><td colspan='2'>[[2cu0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CU0 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cu0 OCA], [http://pdbe.org/2cu0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cu0 RCSB], [http://www.ebi.ac.uk/pdbsum/2cu0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cu0 ProSAT], [http://www.topsan.org/Proteins/RSGI/2cu0 TOPSAN]</span></td></tr>

[[http://www.uniprot.org/uniprot/IMDH_PYRHO IMDH_PYRHO]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).