2y40: Difference between revisions

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<StructureSection load='2y40' size='340' side='right'caption='[[2y40]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2y40' size='340' side='right'caption='[[2y40]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2y40]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y40 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2y40]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y40 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1osi|1osi]], [[1xab|1xab]], [[1g2u|1g2u]], [[1dr0|1dr0]], [[1dpz|1dpz]], [[1osj|1osj]], [[1gc8|1gc8]], [[1xaa|1xaa]], [[1xac|1xac]], [[1dr8|1dr8]], [[1gc9|1gc9]], [[1ipd|1ipd]], [[1xad|1xad]], [[1hex|1hex]], [[2y41|2y41]], [[2y42|2y42]], [[2y3z|2y3z]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1osi|1osi]], [[1xab|1xab]], [[1g2u|1g2u]], [[1dr0|1dr0]], [[1dpz|1dpz]], [[1osj|1osj]], [[1gc8|1gc8]], [[1xaa|1xaa]], [[1xac|1xac]], [[1dr8|1dr8]], [[1gc9|1gc9]], [[1ipd|1ipd]], [[1xad|1xad]], [[1hex|1hex]], [[2y41|2y41]], [[2y42|2y42]], [[2y3z|2y3z]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y40 OCA], [http://pdbe.org/2y40 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y40 RCSB], [http://www.ebi.ac.uk/pdbsum/2y40 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y40 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y40 OCA], [https://pdbe.org/2y40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y40 RCSB], [https://www.ebi.ac.uk/pdbsum/2y40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y40 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LEU3_THET8 LEU3_THET8]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]  
[[https://www.uniprot.org/uniprot/LEU3_THET8 LEU3_THET8]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

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