3a2o: Difference between revisions

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==Crystal Structure of HIV-1 Protease Complexed with KNI-1689==
==Crystal Structure of HIV-1 Protease Complexed with KNI-1689==
<StructureSection load='3a2o' size='340' side='right' caption='[[3a2o]], [[Resolution|resolution]] 0.88&Aring;' scene=''>
<StructureSection load='3a2o' size='340' side='right'caption='[[3a2o]], [[Resolution|resolution]] 0.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3a2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2O FirstGlance]. <br>
<table><tr><td colspan='2'>[[3a2o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A2O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KNJ:(4R)-3-[(2S,3S)-3-{[(4-AMINO-2,6-DIMETHYLPHENOXY)ACETYL]AMINO}-2-HYDROXY-4-PHENYLBUTANOYL]-5,5-DIMETHYL-N-(2-METHYLPROP-2-EN-1-YL)-1,3-THIAZOLIDINE-4-CARBOXAMIDE'>KNJ</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KNJ:(4R)-3-[(2S,3S)-3-{[(4-AMINO-2,6-DIMETHYLPHENOXY)ACETYL]AMINO}-2-HYDROXY-4-PHENYLBUTANOYL]-5,5-DIMETHYL-N-(2-METHYLPROP-2-EN-1-YL)-1,3-THIAZOLIDINE-4-CARBOXAMIDE'>KNJ</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hpx|1hpx]], [[2zye|2zye]], [[3fx5|3fx5]], [[1msm|1msm]], [[1msn|1msn]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hpx|1hpx]], [[2zye|2zye]], [[3fx5|3fx5]], [[1msm|1msm]], [[1msn|1msn]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2o OCA], [http://pdbe.org/3a2o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a2o RCSB], [http://www.ebi.ac.uk/pdbsum/3a2o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2o OCA], [https://pdbe.org/3a2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a2o RCSB], [https://www.ebi.ac.uk/pdbsum/3a2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2o ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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</StructureSection>
</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Large Structures]]
[[Category: Adachi, M]]
[[Category: Adachi, M]]
[[Category: Hidaka, K]]
[[Category: Hidaka, K]]

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