2e4u: Difference between revisions

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<StructureSection load='2e4u' size='340' side='right'caption='[[2e4u]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='2e4u' size='340' side='right'caption='[[2e4u]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2e4u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E4U FirstGlance]. <br>
<table><tr><td colspan='2'>[[2e4u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E4U FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2e4v|2e4v]], [[2e4w|2e4w]], [[2e4x|2e4x]], [[2e4y|2e4y]], [[2e4z|2e4z]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2e4v|2e4v]], [[2e4w|2e4w]], [[2e4x|2e4x]], [[2e4y|2e4y]], [[2e4z|2e4z]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4u OCA], [http://pdbe.org/2e4u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e4u RCSB], [http://www.ebi.ac.uk/pdbsum/2e4u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4u OCA], [https://pdbe.org/2e4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e4u RCSB], [https://www.ebi.ac.uk/pdbsum/2e4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GRM3_RAT GRM3_RAT]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.  
[[https://www.uniprot.org/uniprot/GRM3_RAT GRM3_RAT]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

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