1yu2: Difference between revisions

<table><tr><td colspan='2'>[[1yu2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_bmp-1 Bacteriophage bmp-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YU2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YU2 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yu0|1yu0]], [[1yu1|1yu1]], [[1yu3|1yu3]], [[1yu4|1yu4]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yu2 OCA], [http://pdbe.org/1yu2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yu2 RCSB], [http://www.ebi.ac.uk/pdbsum/1yu2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yu2 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/Q775D6_BPBPP Q775D6_BPBPP]] Tail fiber protein located at the distal ends of the fibers that binds to the adhesion receptors on the host surface, thereby determining the host range. The phage can alter its tropism by modifying this protein. Variants are expressed through a diversity-generating retroelement (DGR) that creates mutant copies of a template repeat and replaces the end of the tail fiber receptor-binding protein with these sequences, thus changing the host range. Milliards of variants of the fiber receptor-binding protein can be created with this system.<ref>PMID:15386016</ref>