1fka: Difference between revisions

Revision as of 16:25, 2 May 2008

STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION

OverviewOverview

The small ribosomal subunit performs the decoding of genetic information during translation. The structure of that from Thermus thermophilus shows that the decoding center, which positions mRNA and three tRNAs, is constructed entirely of RNA. The entrance to the mRNA channel will encircle the message when a latch-like contact closes and contributes to processivity and fidelity. Extended RNA helical elements that run longitudinally through the body transmit structural changes, correlating events at the particle's far end with the cycle of mRNA translocation at the decoding region. 96% of the nucleotides were traced and the main fold of all proteins was determined. The latter are either peripheral or appear to serve as linkers. Some may assist the directionality of translocation.

About this StructureAbout this Structure

1FKA is a Protein complex structure of sequences from Thermus thermophilus. The following page contains interesting information on the relation of 1FKA with [Ribosome]. Full crystallographic information is available from OCA.

ReferenceReference

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution., Schluenzen F, Tocilj A, Zarivach R, Harms J, Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I, Franceschi F, Yonath A, Cell. 2000 Sep 1;102(5):615-23. PMID:11007480 Page seeded by OCA on Fri May 2 16:25:27 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:1fka.gif|left|200px]]
- {{Structure
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-|RELATEDENTRY=[[1c05|1C05]], [[1pkp|1PKP]], [[1ris|1RIS]], [[1rss|1RSS]], [[1an7|1AN7]], [[1a32|1A32]], [[1ekc|1EKC]], [[1qkf|1QKF]]
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fka OCA], [http://www.ebi.ac.uk/pdbsum/1fka PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1fka RCSB]</span>
-}}
 '''STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION'''
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 [[Category: Zarivach, R.]]
 [[Category: 30s ribosomal subunit]]
-[[Category: protein-rna complex]]
+[[Category: Protein-rna complex]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 16:25:27 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:24:34 2008''