3gi5: Difference between revisions
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==Crystal structure of protease inhibitor, KB62 in complex with wild type HIV-1 protease== | ==Crystal structure of protease inhibitor, KB62 in complex with wild type HIV-1 protease== | ||
<StructureSection load='3gi5' size='340' side='right' caption='[[3gi5]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='3gi5' size='340' side='right'caption='[[3gi5]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3gi5]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3gi5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GI5 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K62:(5S)-3-(3-ACETYLPHENYL)-N-[(1S,2R)-3-[(1,3-BENZODIOXOL-5-YLSULFONYL)(2-METHYLPROPYL)AMINO]-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-2-OXO-5-OXAZOLIDINECARBOXAMIDE'>K62</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K62:(5S)-3-(3-ACETYLPHENYL)-N-[(1S,2R)-3-[(1,3-BENZODIOXOL-5-YLSULFONYL)(2-METHYLPROPYL)AMINO]-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-2-OXO-5-OXAZOLIDINECARBOXAMIDE'>K62</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gi4|3gi4]], [[3gi6|3gi6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gi4|3gi4]], [[3gi6|3gi6]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gi5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gi5 OCA], [https://pdbe.org/3gi5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gi5 RCSB], [https://www.ebi.ac.uk/pdbsum/3gi5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gi5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gi/3gi5_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gi/3gi5_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Nalam, M N.L]] | [[Category: Nalam, M N.L]] | ||
[[Category: Schiffer, C A]] | [[Category: Schiffer, C A]] |