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==Crystal structure of the cytochrome P450 CYP121 P346L mutant from M. tuberculosis== | ==Crystal structure of the cytochrome P450 CYP121 P346L mutant from M. tuberculosis== | ||
<StructureSection load='3cxy' size='340' side='right' caption='[[3cxy]], [[Resolution|resolution]] 1.45Å' scene=''> | <StructureSection load='3cxy' size='340' side='right'caption='[[3cxy]], [[Resolution|resolution]] 1.45Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3cxy]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3cxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CXY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1n40|1n40]], [[3cxv|3cxv]], [[3cxx|3cxx]], [[3cxz|3cxz]], [[3cy0|3cy0]], [[3cy1|3cy1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1n40|1n40]], [[3cxv|3cxv]], [[3cxx|3cxx]], [[3cxz|3cxz]], [[3cy0|3cy0]], [[3cy1|3cy1]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp121 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp121 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxy OCA], [https://pdbe.org/3cxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxy RCSB], [https://www.ebi.ac.uk/pdbsum/3cxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
| Line 21: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Cytochrome P450|Cytochrome P450]] | *[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis h37rv]] | [[Category: Mycobacterium tuberculosis h37rv]] | ||
[[Category: Leys, D]] | [[Category: Leys, D]] | ||
Revision as of 22:16, 20 October 2021
Crystal structure of the cytochrome P450 CYP121 P346L mutant from M. tuberculosisCrystal structure of the cytochrome P450 CYP121 P346L mutant from M. tuberculosis
Structural highlights
Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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