1yzm: Difference between revisions

<table><tr><td colspan='2'>[[1yzm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YZM FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yzm OCA], [http://pdbe.org/1yzm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yzm RCSB], [http://www.ebi.ac.uk/pdbsum/1yzm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yzm ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/RBNS5_HUMAN RBNS5_HUMAN]] Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).<ref>PMID:11062261</ref> <ref>PMID:11788822</ref> <ref>PMID:15020713</ref>