HOP protein: Difference between revisions

Michal Harel (talk | contribs)
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Michal Harel (talk | contribs)
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== Function ==
== Function ==


'''HOP protein''' (Hsp70-'''H'''sp90 '''O'''rganizing '''P'''rotein) or '''homeodomain only protein''' functions as a co-chaperone linking Hsp90 and Hsp70<ref>PMID:15382137</ref>.  See details in [[Molecular Playground/Hsp70-Hsp90]].
'''HOP protein''' (Hsp70-'''H'''sp90 '''O'''rganizing '''P'''rotein) or '''homeodomain only protein''' or or '''stress-induced-phosphoprotein 1''' functions as a co-chaperone linking Hsp90 and Hsp70<ref>PMID:15382137</ref>.  See details in [[Molecular Playground/Hsp70-Hsp90]].


== Structural highlights ==
== Structural highlights ==
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[[3fwv]], [[1elr]] – hHOP Tpr2 + Hsp90 peptide – human<br />
[[3fwv]], [[1elr]] – hHOP Tpr2 + Hsp90 peptide – human<br />
[[1elw]] – hHOP Tpr1 + Hsp70 peptide <br />
[[1elw]] – hHOP Tpr1 + Hsp70 peptide <br />
[[2nc9]] – hHOP Tpr2 - NMR<br />
[[3esk]] – hHOP Tpr2 + Hsp70 peptide <br />
[[3esk]] – hHOP Tpr2 + Hsp70 peptide <br />
[[2lni]] – hHOP Tpr3 - NMR <br />
[[2lni]] – hHOP Tpr3 - NMR <br />

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman