1sn4: Difference between revisions

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<StructureSection load='1sn4' size='340' side='right'caption='[[1sn4]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='1sn4' size='340' side='right'caption='[[1sn4]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1sn4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SN4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SN4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1sn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SN4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sn1|1sn1]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sn1|1sn1]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sn4 OCA], [http://pdbe.org/1sn4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sn4 RCSB], [http://www.ebi.ac.uk/pdbsum/1sn4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sn4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sn4 OCA], [https://pdbe.org/1sn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sn4 RCSB], [https://www.ebi.ac.uk/pdbsum/1sn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sn4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SCX9_MESMA SCX9_MESMA]] Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals.  
[[https://www.uniprot.org/uniprot/SCX9_MESMA SCX9_MESMA]] Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

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