1rfb: Difference between revisions

<table><tr><td colspan='2'>[[1rfb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. The August 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Interferons''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_8 10.2210/rcsb_pdb/mom_2010_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RFB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RFB FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rfb OCA], [http://pdbe.org/1rfb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rfb RCSB], [http://www.ebi.ac.uk/pdbsum/1rfb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1rfb ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/IFNG_BOVIN IFNG_BOVIN]] Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.