1kcm: Difference between revisions

<table><tr><td colspan='2'>[[1kcm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KCM FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fvz|1fvz]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kcm OCA], [http://pdbe.org/1kcm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kcm RCSB], [http://www.ebi.ac.uk/pdbsum/1kcm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kcm ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PIPNA_MOUSE PIPNA_MOUSE]] Note=Defects in Pitpna are the cause of the vibrator phenotype which is characterized by early-onset progressive action tremor, degeneration of brain stem and spinal cord neurons, and juvenile death. The mutation is due to the insertion of an intracisternal A particle retrotransposon in intron 4 which results in a 5-fold reduction in protein levels.  

[[http://www.uniprot.org/uniprot/PIPNA_MOUSE PIPNA_MOUSE]] Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.