Growth factors: Difference between revisions
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**[[Tumor necrosis factor receptor]] | **[[Tumor necrosis factor receptor]] | ||
**[[Tumor necrosis factor ligand superfamily]] | **[[Tumor necrosis factor ligand superfamily]] | ||
The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains (CRD). The <scene name='59/590824/Cv/8'>CRD domains are ca. 40 amino-acid long and contain 4-6 cysteine residues</scene>. The CRDs are involved in binding of TNF<ref>PMID:8939750</ref>. <scene name='59/590824/Cv/9'>Mg coordination site</scene>. Water molecules are shown as red spheres. | |||
**[[TRAIL|TRAIL (TNF-related apoptosis-inducing ligand) or TNF ligand superfamily 10]] | |||
'''TRAIL-R2''' is called '''DR5'''. <scene name='48/480878/Cv/3'>TRAIL trimer residues complex with death receptor-5 extracellular domain</scene> ([[1d0g]]). | |||
*[[Vascular Endothelial Growth Factor]] and [[Vascular Endothelial Growth Factor Receptor]] (VEGFR). VEGFR belongs to [[Receptor tyrosine kinases]], class IV. | *[[Vascular Endothelial Growth Factor]] and [[Vascular Endothelial Growth Factor Receptor]] (VEGFR). VEGFR belongs to [[Receptor tyrosine kinases]], class IV. | ||
*[[TGF-beta receptor|Transforming Growth Factor and its receptor]] | *[[TGF-beta receptor|Transforming Growth Factor and its receptor]] | ||